Bioinformatics @ TU Delft

Journey to the frontier of computational Biology. Master bioinformatics software and computational approaches in modern biology.

About this course

How do we sequence and compare genomes? How do we identify the genetic basis for disease? How do we construct an evolutionary Tree of Life for all species on Earth?

When you complete this interactive textbook, you will learn how to answer many questions in modern biology that have become inseparable from the fundamental algorithms used to answer these questions.

We recommend taking the modules in the order presented, as each subsequent module will build on material from previous modules .

If you're interested in a print companion of this textbook, you can find one at

This course is intended for TU Delft students.

For the NB2161 - 2019-2020 course you are expected to complete these modules:

1. Where in the Genome Does Replication Begin?
3. How Do We Assemble Genomes?
5. How Do We Compare Biological Sequences?
7. Which Animal Gave Us SARS?
8. How Did Yeast Become a Wine Maker?
9. How Do We Locate Disease-Causing Mutations?

All other modules should be hidden and become available Sept. 1, 2020


Who is this course for

Learners who are interested in seeing the fundamental algorithms that have made biology into a computational discipline.

Learners should be good technical thinkers and have  introductory knowledge of programming. 

Meet the Instructors

Course content




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