What you will learn
- choose the optimal ways and methods for the solutions of both experimental and theoretical problems
- discuss and interpret the results of investigations
- navigate in the modern literature on organic chemistry
- hold a scientic discussion on problems of Chemistry of Heterocyclic Compounds
- pose a problem for an investigation without assistance
About this course
The course provides an extensive introduction into heterocyclic chemistry. Special emphasis is given to the core heterocyclic systems, such as 5-membered heterocycles (pyrrole, furane, thiophene), indole, pyridine, quinoline and isoquinoline. For each type of heterocycles, electronic structure, methods for the ring synthesis, chemical properties and characteristic reactions will be discussed. The concept of heteroaromaticity, general methods for ring synthesis (by a number of cyclisation and cycloadditon reactions) as well as different systems for nomenclature will be presented. The course aim is to give a fundamental theoretical understanding of heterocyclic chemistry, including alternative general methods for ring construction and the application of such methods for the preparation of specific groups of heterocyclic systems. You will get conversant with peculiar properties and reactions for the most important heterocyclic compounds as well as different systems of nomenclature for heterocycles.
6 chapters with the following educational content:
Chapters
- Introduction (notion of Heterocyclic chemistry, Classification of heterocyclic compounds), Four-membered heterocyclic compounds
- Five-membered heterocyclic compounds with one heteroatom. Synthesis
- Five-membered heterocyclic compounds with one heteroatom. Chemical Properties
- Indole, Isatine
- Pyridine, Quinoline and Isoquinoline
- Pyridazine, Pyrimidine and Pyrazine
Whom this course is for
First of all, for the organic chemistry students (master’s degree or graduate students) interested in peculiar properties and reactions for the most important heterocyclic compounds as well as dierent systems of nomenclature for heterocycles. But we also recommend this course for students of related elds: medical chemistry, pharmaceutical analysis.
Initial requirements
You will need a basic knowledge of organic chemistry. However, we have tried to make the course as easy for understanding as possible and oer a demonstrative selection of information, as well as links to additional resources.
Meet the Instructors
How you will learn
This course has 6 modules:
Module 1: Classication of heterocyclic compounds and Four-membered heterocyclic compounds
Module 2: Five-membered heterocyclic compounds with one heteroatom. Synthesis
Module 3: Five-membered heterocyclic compounds with one heteroatom. Chemical Properties
Module 4: Indole and Isatine
Module 5: Pyridine, Quinoline and Isoquinoline
Module 6: Pyridazine, Pyrimidine and Pyrazine